A lot of people have strong feelings when
they hear clinical trial, thinking ‘oh, it’s just because
I’ve exhausted other options,’ and I want to
emphasize that is not the case. If someone has one of these genetic changes
that is actionable, where we know a lot about it,
but it’s not approved yet, I would argue that
for those people, depending on what the target is, sometimes a clinical trial may be the
most appropriate very first therapy.